UniProt ID Q16543
Protein Name Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co
-chaperone Cdc37, N-terminally processed]
Gene Name CDC37
Position 13
SequenceWindow VWDHIEVSDDEDETH
Function Score? 0.999
Disorder score? 0.546 Disordered
Protein-Targeted Drug

SODIUM MOLYBDATE; GELDANAMYCIN

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Protein Subcellular Localization

Cytoplasm {ECO:0000269|PubMed:9482106}.

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Protein Function

Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233). Inhibits HSP90AA1 ATPase activity (PubMed:23569206). {ECO:0000269|PubMed:23569206, ECO:0000269|PubMed:8666233}.

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Functional domains

Distribution of Tumor Phosphorylation Levels (corrected without protein) in Pan-Cancer

No Data

Distribution of Tumor Phosphorylation Levels (corrected with protein) in Pan-Cancer

No Data

Distribution of Normal Phosphorylation Levels (corrected without protein) in Pan-Cancer

No Data

Distribution of Normal Phosphorylation Levels (corrected with protein) in Pan-Cancer

No Data