Phosphosite: 13 in Q16543
| UniProt ID | Q16543 |
|---|---|
| Protein Name |
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co -chaperone Cdc37, N-terminally processed] |
| Gene Name | CDC37 |
| Position | 13 |
| SequenceWindow | VWDHIEVSDDEDETH |
| Function Score? | 0.999 |
| Disorder score? | 0.546 Disordered |
| Protein-Targeted Drug | SODIUM MOLYBDATE; GELDANAMYCIN . . . more
|
| Protein Subcellular Localization | Cytoplasm {ECO:0000269|PubMed:9482106}. . . . more
|
| Protein Function | Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233). Inhibits HSP90AA1 ATPase activity (PubMed:23569206). {ECO:0000269|PubMed:23569206, ECO:0000269|PubMed:8666233}. . . . more
|
| Functional domains |
Distribution of Tumor Phosphorylation Levels (corrected without protein) in Pan-Cancer
Distribution of Tumor Phosphorylation Levels (corrected with protein) in Pan-Cancer
Distribution of Normal Phosphorylation Levels (corrected without protein) in Pan-Cancer
Distribution of Normal Phosphorylation Levels (corrected with protein) in Pan-Cancer
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